Thymic carcinoma are uncommon neoplasms, with a particular predilection for pleural disease localizations, that could be treated by extended pleurectomy/decortication. This surgical procedure can be followed by cardiovascular, pleuropulmonary and technical complications, with an acute or late onset (months/years). In this case, a woman 55–years–old with metastatic thimic carcinoma underwent to radical thymectomy, left superior pulmonary lobectomy and left extended pleurectomy/decortication with diaphragmatic prosthesis placement. After 8 years, diaphragmatic prosthesis rupture and empyema were diagnosed at imaging examinations (Computed Tomography and videofluoroscopic swallowing study).