Volume : VI, Issue : VIII, August - 2017

A COMPARATIVE EVALUATION OF TETRACYCLINE CONTAINING MICROSPHERES AND COMMERCIALLY AVAILABLE TETRACYCLINE FIBERS TO EVALUATE THEIR EFFICACY IN PERIODONTAL POCKET THERAPY - A CLINICAL AND MICROBIOLOGICAL STUDY

Dr. Manish Kumar, Dr. Mona Sharma, Dr. Vivek Govila, Dr. Vineeta Mittal, Prof. Dr. Shailendra K. Saraf

Abstract :

 The aim of this clinical trial was to compare the efficacy of Tetracycline containing

 Microspheres (TM) and commercially available tetracycline containing Fibers (TF) as local

 drug-delivery system in the treatment of periodontal pocket therapy. A randomized split mouth design was adopted  for allocating, 50 sites in different treatment modalities : SRP + TF and SRP + TM. Periodontal Plus AB was used for TF group and prepared microsphere containing Tetracycline was used for TM group. Clinical parameters were seen at baseline, 1  and 6 months and microbiological analysis was done at baseline and 3 months. Clinical parameters that were recorded were PI, GI, PD and RAL. In microbiological analysis, CFU of Prevotella Intermedia were seen. The result revealed that both  groups showed a statistically significant reduction in clinical parameters and microbiological parameters  at 1, 3 and 6 months compared to baseline and TM was more effective in comparison to TF. 

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Dr. Manish kumar, Dr. Mona Sharma, Dr. Vivek govila, Dr. Vineeta Mittal, Prof.(Dr.) Shailendra K. Saraf, A COMPARATIVE EVALUATION OF TETRACYCLINE CONTAINING MICROSPHERES AND COMMERCIALLY AVAILABLE TETRACYCLINE FIBERS TO EVALUATE THEIR EFFICACY IN PERIODONTAL POCKET THERAPY‾A CLINICAL AND MICROBIOLOGICAL STUDY, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : VOLUME-6, ISSUE-8, AUGUST-2017


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