A Facile Protocol To The Hetero- Annulation Of Face �A� Of Pyridine Condensed Benzazepinone With Thiazolidine Nucleus

Aditi; Yadav Yogita; Singh Rajendra

Volume : V, Issue : IX, September - 2016

A Facile Protocol To The Hetero- Annulation Of Face �A� Of Pyridine Condensed Benzazepinone With Thiazolidine Nucleus

Aditi, Yadav Yogita, Singh Rajendra

Abstract :

A Facile protocol to the hetero- annulation of face �a� of pyridine condensed benzazepinone with thiazolidine nucleus through its 2-iminothiol function (6) has been described. The synthesis of thiazolidino annulated analogues 7-10 was achieved by exploiting the propensity of azomethine group containing a 2-thiomethylether function, in its nucleophilic displacement reactions with ethylchloroacetate, chloroacetone, 2-chlorocyclohexanone and N-phenyl-2-omo-4-piperidone respectively [scheme-1,2]