A Study On Clinical, Electrophysiological Subtypes And Seasonal Variations Of Guillain Barr� Syndrome In Central Tamil Nadu In Two Years.

Elangovan S; Thangraj M; Balamurali K; Arunkumar M

Volume : VI, Issue : XI, November - 2017

A Study On Clinical, Electrophysiological Subtypes And Seasonal Variations Of Guillain Barr� Syndrome In Central Tamil Nadu In Two Years.

Elangovan S, Thangraj M, Balamurali K, Arunkumar M

Abstract :

Guillain barr� syndrome is an acute autoimmune disease causing flaccid paralysis and having a good prognosis with modern treatment. The clinical course and prognosis is variable in different clinical and electrophysiological types. Our aim was to study clinical, electrophysiological subtypes and seasonal variations amongst the patients with GBS admitted in two years in Thanjavur Medical College Hospital in Central Tamil Nadu.

Materials And Methods:

A Retrospective study of 95 patients with Acute Guillain barr� syndrome (Acute inflammatory demyelinating polyradiculoneuropathy) who fulfilled Asberry�s criteria was conducted. We extracted data from the Thanjavur medical college hospital records retrospectively over a two year period (January 2015 to December 2016). The patients were divided in to four seasonal groups: S1 (spring -Feuary to April), S2 (summer- May to July), S3 (rainy -August to October), S4 (winter- November to January) and parameters were studied.

Results:

From 92 cases of GBS 56 (60.87%) were male and 36 (39.13%) were female with a M: F ratio being 1: 0.64. Summer and winter had the most GBS cases. Most of the patients were admitted in the months of July (15), December (11), Feuary (10) and June (9). Most common clinical type of GBS seen in the studied cases was pure motor (84.78%) followed by motor sensory (11.96%), miller fisher (2.17%) and pure sensory (1.08%). Classical AIDP (Pure motor-Demyelinating) was the commonest type (>76%) followed by AMSAN Variant (17%)

Conclusion:

Our study shows that there is significant seasonal variation and type of GBS occurring in Tamil Nadu. Our study showed that there was more incidence of GBS in July and December months. There were summer and winter peaks observed which has to be correlated with epidemiological data about prevalent viral infections and serological studies.