ANALYSIS OF CSF PLEOCYTOSIS IN A TERTIARY CARE HOSPITAL

Dr. Atif Rasool Kawoosa; Dr. Fiza Parvez Khan; Dr. Subuh Parvez Khan; Dr. Nusrat Bashir

Volume : VIII, Issue : IV, April - 2019

ANALYSIS OF CSF PLEOCYTOSIS IN A TERTIARY CARE HOSPITAL

Dr. Atif Rasool Kawoosa, Dr. Fiza Parvez Khan, Dr. Subuh Parvez Khan, Dr. Nusrat Bashir

Abstract :

BACKGROUND: Cereospinal fluid is an important fluid for forming a diagnosis in a considerable amount of patients admitted under internal medicine and neurology. We aimed to study the pattern of CSF Cell Analysis at our Tertiary care Hospital. MATERIALS AND METHODS: This study spanning over a period of one year was conducted in a tertiary care hospital, evaluating the findings in cereospinal fluid from both adult and paediatric in-patients. RESULTS: A total of 260 samples including 108 adults and 152 paediatric cases were studied. Normal cell counts were observed in 168 cases and pleocytosis in the remaining. One case of epithelial malignancy metastasizing to CNS was also identified. A traumatic tap was observed in two patients. Differential counts showed the predominance of lymphocytes at lower cell counts (< 100 cells/micl) and a predominance of Neutrophils at higher cell counts (> 100 cells/ micl). CONCLUSION: CSF Cell Analysis is a common investigation done in neurology in-patients, both adults and children. A significant proportion of cases have normal cell counts which is often clinically relevant. The type of cells, although depends mainly on the clinical scenario, seems to vary with total cell count also, with lymphocytes predominating at lower and neutrophils at higher total counts. Monocytes were detected at intermediate cell counts only.