Global Journal For Research Analysis (GJRA)

Dr. Sunil S. Yadav

Volume : VI, Issue : IV, April - 2017

Antibacterial study and effect on glucoamylase in vitro of aqueous and ethyl acetate extracts of Syzygium cumini seeds

Dr. Sunil S. Yadav

Abstract :

Antibacterial and glucoamylase inhibitory effect of aqueous and ethyl acetate extracts isolated at different temperatures from seeds of Syzigium cumini is studied in vitro. Both aqueous and ethyl acetate extracts are antibacterial against E. Coli, B. Subtilis, P. Aeruginosa and S. Aureus. The aqueous extract isolated at 25⁰C and ethyl acetate extract isolated at 10⁰C showed 35% and 50% of maximum inhibition of glucoamylase respectively. Water extracts of Syzigium cumini seed are low inhibitors of glucoamylase than ethyl acetate extracts. We observed that water extract isolated at 25^oC is moderate inhibitor of glucoamylase. Even though the extraction yield with ethyl acetate is less but inhibition of glucoamylase is greater . Thus we conclude that ethyl acetate extract of Syzigium cumini seed is potent inhibitor of glucoamylase and hence hypoglycaemic than aqueous extracts in diabetes type-2.