Volume : IV, Issue : IV, April - 2015

Antioxidant Effect of vitamin A & E on Heavy metal (Cd) Induced Renal, Testicular as well as Hepatic injury in Male Albino mice

Rajesh Ku. Meher, Namita Nayak, Bhaskar Behera

Abstract :

 Heavy metal toxicity is world threatening problem for human as well as other organism. Heavy metal is widely 

distributed in environment and some of them occur in food, water, air. Exposure of heavy metal induced oxidative 
stress and renal and testicular as well as hepatic injury were evaluated in male mice. Present study is desired to find out 
whether vitamin A & E is able to protect the heavy metal (Cd) stress injury to kidney, liver, testicular abnormality. For these purpose 15 numbers of 
male albino mice were taken and acclimatization on laboratory condition for about 15 days. 15 mice were divided in to 3 different group each 
group contain 5 mice first group served as control and was given only distilled water, the second group received distilled water supplemented 
with Cd 10mg per Kg body weight, third group received distilled water supplemented with 10 mg Cd/kg body weight with Vitamin Cd/kg per day 
for 90 days. Tissue were collected from both control and treated animals and studied. Mice exposure to Cd show histopathological changes in the 
liver, kidney, testis but not in Cd supplemented with vitamin A & E
 

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Rajesh Ku. Meher, Namita Nayak, Bhaskar Behera Antioxidant Effect of vitamin A & E on Heavy metal (Cd) Induced Renal, Testicular as well as Hepatic injury in Male Albino mice Global Journal For Research Analysis, Vol: 4, Issue: 4 April 2015


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