Clinical Assessment of the effects of Prostaglandin E1 on Orthodontic Tooth Movement in Maxillary Arch: An In vivo Split Mouth Study

Dr. Swati Jain; Dr. Nishitha C. Gowda; Dr. Vennila N. Swamy; Dr. Santosh Ramegowda

Volume : VI, Issue : V, May - 2017

Clinical Assessment of the effects of Prostaglandin E1 on Orthodontic Tooth Movement in Maxillary Arch: An In vivo Split Mouth Study

Dr. Swati Jain, Dr. Nishitha C. Gowda, Dr. Vennila N. Swamy, Dr. Santosh Ramegowda

Abstract :

Clinical Assessment of the effects of Prostaglandin E1 on Orthodontic Tooth Movement in Maxillary Arch: An In vivo Split Mouth Study

Introduction: Prostaglandins are one of the chemical mediators influencing the orthodontic tooth movement. (OTM)

Aim: To study the effect of exogenous application of Prostaglandin E1 (PgE1) gel on OTM in routine patients.

Methodology: Fifteen patients were selected who required extraction of first premolars for the correction of malocclusion. After routine banding, bonding, initial alignment, en-mass retraction using appropriate appliances, they were treated with topical application of 3 microgram of PGE1 gel on test side and placebo gel on control side in four sessions. The OTM was measured clinically on patients and models.

Results: There was statistically significant increase in OTM on test side as compared with control side.

Conclusion: PGE1gel is an effective method for faster OTM.