FETOMATERNAL OUTCOME IN SICKLE CELL HEMOGLOBINOPATHY

Prof Dr Tushar Jyoti Kar; Dr Lina Baru; Dr Ganeshram Bhoi; Dr Ranjita Patnaik

Volume : VII, Issue : II, February - 2018

FETOMATERNAL OUTCOME IN SICKLE CELL HEMOGLOBINOPATHY

Prof Dr Tushar Jyoti Kar, Dr Lina Baru, Dr Ganeshram Bhoi, Dr Ranjita Patnaik

Abstract :

Background- Ours is a tertiary care hospital with a catchment area of Odisha & part of Chattishgarh has high prevalence of sickle cell hemoglobinopathy .

Method- A prospective case control study of two years duration with sample comprised of 2040 pregnant women attending O&G OPD & LR .

Result-Out of 2040 women 98(4.8%) had sickle cell hemoglobinopathy, with sickle cell disease SS(n=32) 1.56% & sickle cell trait AS(n=66) 3.23%.There was increased risk of complications in women with (SS) like crisis(25%), PIH ( 28.1%) ,anemia (100%) ,UTI (31.25%) ,PPH (25%) ,IUGR (18.8%), need of blood transfusion (40.6%), maternal mortality (12.5%) , LBW (65.5%), low apgar score (17.9%) & NICU admissions(28.57%) respectively as compared to women with (AS) where crisis (3%) , PIH (6%) ,anemia (95.5%),UTI(19.7%) ,PPH (9.5%) ,IUGR (7.6%), need of blood transfusion (6.1%), no maternal mortality , LBW (28.8%),low apgar score (3%) and NICU admissions(10.6%) respectively.

Conclusion-The rate of complication is high in SS case. Screening and early, aggressive and comprehensive Antenatal & perinatal care can improve fetomaternal outcome.