INCIDENCE OF BONE MARROW FINDINGS IN HEMATOLOGICAL DISORDERS BASED ON AGE AND GENDER  : AN OBSERVATIONAL STUDY

Dr Sharique Ahmad; Dr Shoaib Irfan; Dr Pankhudi Gupta; Prof Syed Riaz Mehdi; Dr Zeashan Haider Zaidi

Volume : V, Issue : IV, April - 2016

INCIDENCE OF BONE MARROW FINDINGS IN HEMATOLOGICAL DISORDERS BASED ON AGE AND GENDER : AN OBSERVATIONAL STUDY

Dr Sharique Ahmad, Dr Shoaib Irfan, Dr Pankhudi Gupta, Prof Syed Riaz Mehdi, Dr Zeashan Haider Zaidi

Abstract :

<p>&nbsp;Bone marrow examination is useful in the diagnosis of both haematological and non haematological disorders. Indications have included the diagnosis, staging, and therapeutic monitoring for lymphoproliferative disorders such as chronic lymphocytic leukemia, Hodgkin&rsquo;s and non-Hodgkin&rsquo;s lymphoma, hairy cell leukaemia, and multiple myeloma. Furthermore, evaluation of cytopenia, thrombocytosis, leukocytosis, anaemia, and iron status can also be done. This is also an important tool in the diagnosis of non-haematological disorders like storage diseases, granulomatous lesions, metastatic carcinoma, Pyrexia of unknown origin (PUO), and disseminated infection in immunocompromised hosts. The two most important techniques used for the diagnosis are bone marrow aspiration and bone marrow trephine biopsy which are complementary to each other. Aspiration of the marrow is primarily utilised for cytological assessment with analysis directed towards morphology and obtaining a differential cell count. Biopsy is essential for diagnosis in a dry tap or blood tap which occurs when the marrow is fiotic or densely cellular. In the present study, consecutive three years of indoor patients with hematological disorders based upon age and gender were evaluated for the clinical diagnosis by doing bone marrow aspiration and bone marrow trephine biopsy in a Medical College Hospital.</p>