Laboratory Markers of Gastric Intestinal Metaplasia

Raziye Turan; Tugrul Kesicioglu; Ahmet Cumhur Dulger; Demet Sengul

Volume : VIII, Issue : II, February - 2019

Laboratory Markers of Gastric Intestinal Metaplasia

Raziye Turan, Tugrul Kesicioglu, Ahmet Cumhur Dulger, Demet Sengul

Abstract :

With increasing number of patients diagnosed with gastric cancer screening is gaining more importance. Risk factors of gastric intestinal metaplasia has been reported as presence of Helicobacter pylori infection, older ages, smoking history, taking spicy food, occupation status and the presence of IL10-592 C/A. At total; 85 patients were enrolled in the period of May 2018-August 2018, laboratory results and abdominal ultrasound were collected. There were taken gastric biopsies in patients who underwent gastroscopy beause of other reasons. All gastroscopies were performed with Fujinon-Videoscopes (Tokyo, Japan). Non-alcoholic fatty liver disease (NAFLD) was determined with the abdominal ultrasonography. A possible relationship between NAFLD and intestinal metaplasia was investigated. Using laboratory parameters we could not testify any relation between NAFLD and intestinal metaplasia, regarding Helicobacter pylori-status, lipid-and diabetes parameters. Significant differences were found in patients with intestinal metaplasia in terms of lower ferritin and higher TSH values. Perhaps these parameters could be used in order to identify patients with intestinal metaplasia, further studies are needed to verify these results.