Global Journal For Research Analysis (GJRA)

Dr. KHAIRE SUREKHA D.

Volume : VI, Issue : V, May - 2017

Oncocytic variant of papillary carcinoma of thyroid -A Diagnostic challenge in Cytology.

Dr. Khaire Surekha D.

Abstract :

Oncocytic variant of papillary carcinoma of thyroid is a rare case .Neoplastic and nonneoplastic hurthle cell rich lesions of thyroid has cytological overlapping features and different clinical behavior and management . so despite the ease of recognising hurthle cells on routine cytology smears, they can pose substantial diagnostic challenge to cytopathologists .A 23 year old female presented with thyroid swelling which was diagnosed as Hurthle cell neoplasm -Bethesda Category IV on FNAC.Histopathology showed an encapsulated tumour composed of follicles and papillae lined by large cells with abundant granular cytoplasm and nuclear features of PTC. We diagnosed as an oncocytic variant of papillary carcinoma of thyroid . A possibility of oncocytic variant of papillary thyroid carcinoma should always be considered by pathologist and needs to be differentiated from hurthle cell neoplasm and other hurthle cell rich lesions as its clinical behavior and management is different. Histopathological examination of an entire lesion remains the gold standard for correct diagnosis .