Global Journal For Research Analysis (GJRA)

Dr. Yasha Upendra; Dr. Naveen Keswani; Dr. Sampreeti Sendur; Dr. Abhishek Pallava

Volume : VI, Issue : III, March - 2017

Prevalence of dermatoses among naxal infested tribal villagers: A community based study from South Chhattisgarh, India

Dr. Yasha Upendra, Dr. Naveen Keswani, Dr. Sampreeti Sendur, Dr. Abhishek Pallava

Abstract :

Background: Hypertension is one among the leading disease causing morbidity and mortality irrespective of other co morbid conditions. Hypothetically the culprit behind has been the accumulation of free radicals causing oxidative stress. Oxidative stress plays a vital role in pathophysiological changes in hypertension. Prescribing 2 or 3 medications is one among the cause for major drug interaction and hence to prevent it, necessity of the pertained drug for the disease to act as a scavenger is the need of the hour in current scenario. Objective: In this study we are intended to find antihypertensive drug Carvedilol (3.125mg) percentage of scavenging action of nitric oxide radicals against the standard ascorbic acid and commercially available vitamin C. Result: It is found that the nitric oxide scavenging activity of Carvedilol (3.125) is quite appreciable (75.74%) when compared to ascorbic acid (98.5%) and Vit C(90.58%).