Volume : VII, Issue : VI, June - 2018

PSORIASIS AND THYROID: A RETROSPECTIVE RESEARCH FROM TURKEY

Dr. Atil Avci, Dr. Deniz Avci

Abstract :

AİM

Psoriasis is a chronic, inflammatory and immuno-mediated skin disease. Many autoimmune diseases have been reported with psoriasis such as autoimmune thyroiditis. Although the relationship between psoriasis and thyroid has been repeatedly studied and over-emphasized, this relationship has not yet been fully elucidated.

PATIENTS AND METHOD

The study was carried out with a retrospective review of the files of psoriasis patients (n=82) and healty controls (n=47) admitted to the Dermatology clinics. Age, gender, serum anti-TPO levels, anti-TG levels, thyroid stimulating hormone (TSH) levels, free T3 levels and free t4 levels were corresponden between the two groups.

RESULTS

The median anti-TPO level of psoriatic patients was 5.6 (0.1-1300) IU/L. In the control group, the median anti TPO level was 1.30 (0.2-727.6) IU/L. The difference was statistically significant (p <0.001).

The median anti-TG level of psoriatic patients was 3.65 (0.1-310) IU/L. The median anti-TG level of healthy controls was 2.20 (2.20-511.2) IU/L. The difference was statistically significant (p=0.001).

The mean free T3 level of patients with psoriasis was 2.56 (0.63-4.52) IU/L. In healthy controls this level was 3.11 (1.70-4.44) IU/L. There was a statistically significant difference (p=0.002).

CONCLUSION

In our view, the relationship between these two diseases can be better elucidated by extensive studies on pathogenesis.

Keywords :

Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Dr. Atil AVCI, Dr. Deniz AVCI, PSORIASIS AND THYROID: A RETROSPECTIVE RESEARCH FROM TURKEY, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7 | Issue-6 | June-2018

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