ROLE OF COLOR DOPPLER ULTRASONOGRAPHY IN PREDICTION & EARLY DETECTION OF PRE- ECLAMPTIC TOXEMIA

Dr. Preeti Dubey; Dr. Rashmi Gupta; Dr Vinita Malhotra

Volume : VIII, Issue : V, May - 2019

ROLE OF COLOR DOPPLER ULTRASONOGRAPHY IN PREDICTION & EARLY DETECTION OF PRE- ECLAMPTIC TOXEMIA

Dr. Preeti Dubey, Dr. Rashmi Gupta, Dr Vinita Malhotra

Abstract :

Introduction-Pre-eclampsia is a pregnancy specific multisystem disorder of unknown etiology. It affects 5-7% of pregnancies and a significant cause of maternal and fetal morbidity and mortality. Doppler ultrasonography offers safe and noninvasive technology for prediction and early detection of disease. Aims & objectives- To evaluate role of Doppler ultra-sonography in prediction of pre eclamptic toxemia in early pregnancy. Material &methods- It was blind prospective study done in 100 pregnant patients in their second trimester with singleton pregnancy attending outdoor and indoor department of UISEMH GSVM Medical College Kanpur. A detailed B mode ultra-sonographic study done after ruling out fetal congenital malformation. Doppler indices were evaluated in uterine artery, umbilical artery and middle cereal artery. Results- uterine artery notch was present in 15.7% patients in whom 54.5% develop pre-eclampsia subsequently. Uterine artery PI in pre eclamptic patients was 1.5922+_0.2610 and in normotensive it was 1.3475+_0.1925. The difference of PI between these two group was statically significant (p=0.0011). In this study mean umbilical artery S/D ratio in pre eclamptic pts was 4.9256+_1.5049 and in normotensive group it was 3.8895+_1.7439. The mean difference of S/D ratio between these two groups was statistically significant (p=0.0047) Conclusion-Uterine artery notch, uterine artery PI and umbilical artery S/D ratio are reasonable predictor of women at risk of developing pre eclamptic toxemia. Out of these uterine artery notch is best predictor followed by uterine artery PI.