SEROPREVALENCE OF TOXOPLASMA AND RUBELLA INFECTIONS IN BAD OBSTETRIC HISTORY PATIENTS AT A TERTIARY CARE HOSPITAL

Anita E. Chand; Namita Garg; Sarita Rawat

Volume : VI, Issue : IV, April - 2017

SEROPREVALENCE OF TOXOPLASMA AND RUBELLA INFECTIONS IN BAD OBSTETRIC HISTORY PATIENTS AT A TERTIARY CARE HOSPITAL

Anita E. Chand, Namita Garg, Sarita Rawat

Abstract :

Introduction: Toxoplasma gondii and Rubella virus infections are one of the contributing causes of Bad Obstetric History . These infections in pregnancy results in various congenital malformations, adverse outcome of foetus & pregnancy. Objective:To evaluate the seroprevalence of Toxoplasma gondii and Rubella virus infections in women with Bad Obstetric History patients. Materials & Methods :.Determination of Toxoplasma and Rubella IgM &IgG antibodies was done in the serum samples collected from BOH patients using ELFA (Enzyme Linked Flourescent Assay ) technique on mini VIDAS. Results: Out of total 100 BOH patients included in the study, seroprevalence of Toxo IgM was 2%,Toxo IgG was 6%, Rubella IgM was 2% and Rubella IgG was 84%. Conclusion:In order to prevent adverse effects of Toxoplasma and Rubella infections on pregnancy and foetus, routine screening for these infections in antenatal cases with bad obstetric history should be carried out for early diagnosis & appropriate management.