Study Of The Correlation Between Microalbuminuria and Retinopathy,Lipid Profile In Patients Of Essential Hypertension

Dr.Papaiah Nirmal Pudota

Volume : VIII, Issue : XI, November - 2019

Study Of The Correlation Between Microalbuminuria and Retinopathy,Lipid Profile In Patients Of Essential Hypertension

Dr. Papaiah Nirmal Pudota

Abstract :

Objective:To detect the Correlation of microalbuminuria in 100 hypertensive patients with Retinopathy and lipid profile Methods:We performed a prospective analysis study of 100 patients visiting Balaji medical college and hospital,Chennai.Inclusion criteria :Hypertensive patients with BP>140/90 mmhg and age more than 30 years.Exclusion criteria:Patients with renal disease,T2DM,Ischemic heart disease,CVA,pregnancy.microalbuminuria was measured using the dip stick test ,defined as having UAE in the range of 30-300mg/24h Results:100 patients were involved in the study fulfilling the criteria.30 out of 100 patients had microalbuminuria. 21 males out of 45 were found to have microalbuminuria and 9 out of 25 females were found to have Microalbuminuria.Serum levels of cholesterol,Triglycerides,and uric acid in patients with microalbuminuria were higher than the levels in those with normal UAE(urine albumin excretion),and HDL(high density lipid) levels in patients with MA(microalbuminuria)were lower than levels in patient with normal UAE.On performing Fundus examination in the study patients ,13 out of 22 patients with grade II retinopathy had microalbuminuria and 8 out of 13 with stage III retinopathy had microalbuminuria ,5 out of 9 with stage IV had MA,and only 2 out of 43 patients with normal fundus had MA.So,Stage II,III,IVof retinopathy patients had more frequency of microalbuminuria compared to patients with normal fundus. Therefore screening of fundus is a must for patients having MA,so if we could detect MA early,end organ damage could be prevented by appropriate clinical management Conclusion Hypertension is one of the most common global diseases causing significant mortality and morbidity.Therefore proper screening and assessment is required to identify patients at risk.Patients with Microalbuminuria have increased chances of developing retinopathy compared to those without.So, screening for microalbuminuria must be considered to be part of initial work up in every hypertensive patient and those with MA must be screened regularly for fundus along with appropriate clinical management.