Volume : V, Issue : XI, November - 2016

THE EFFECT OF TRANEXAMIC ACID IN CONTROLLING PERI OPERATIVE BLOOD LOSS:

Dr B Ravi, Dr Saranya Ravi

Abstract :

 TRANEXAMIC ACID IS AN ANTI FIBRINOLYTIC DRUG USED FOR PROMOTING CLOT FORMATION IN THE SETTING OF MASSIVE HAEMORRHAGE WITH SUSPECTED NEED FOR MASSIVE BLOOD TRANSFUSION(CLINICAL EVIDENCE OF MARKED BLOOD LOSS-INTERNAL OR EXTERNAL,SUSTAINED TACHYCARDIA AND HYPO TENSION. ) TRANEXAMIC ACID IS CONTRA INDICATED IN NON HAEMORRHAGIC SHOCK,NON TRAUMATIC BLOOD LOSS AND HAEMORRHAGIC LOSS STABILISED WITH OTHER HAEMOSTATIC AGENTS/MEASURES. THE EXACT TIME OF ONSET IS NOT CLEAR AFTER INTRA VENOUS ADMINISTRATION WITH DELAYED EFFECTS UPTO 48 HOURS CONSISTENT WITH ANTI INFLAMMATORY ACTIONS.IT’S THEORETICAL CONCERN ,TXA HAS NOT BEEN SHOWN TO CAUSE SIGNIFICANT INCREASE IN DVT,PULMONARY EMBOLISM,MYOCARDIAL INFORCTION OR STROKE IN PUBLISHED TRIALS TO DATE.TXA IS ADMINISTERED AS 1 GRAM IV OVER 10 MINUTES IN 100 ML OR 250 ML NORMAL SALINE

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

DR B RAVI, DR SARANYA RAVI, THE EFFECT OF TRANEXAMIC ACID IN CONTROLLING PERI OPERATIVE BLOOD LOSS:, Global Journal For Research Analysis,Volume : 5 | Issue : 11 | November 2016

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