A CLINICAL COMPARATIVE STUDY OF INHALATIONAL SEVOFLURANE AND INTRAVENOUS PROPOFOL FOR LARYNGEAL MASK AIRWAY ANAESTHESIA IN PAEDIATRIC PATIENTS

Deba Gopal Pathak; Kumar Jyoti Deb

Volume : VIII, Issue : III, March - 2019

A CLINICAL COMPARATIVE STUDY OF INHALATIONAL SEVOFLURANE AND INTRAVENOUS PROPOFOL FOR LARYNGEAL MASK AIRWAY ANAESTHESIA IN PAEDIATRIC PATIENTS

Deba Gopal Pathak, Kumar Jyoti Deb

Abstract :

Objective: To compare effectiveness of inhalational sevoflurane and intravenous (IV) propofol anaesthesia with the laryngeal mask airway (LMA) in children undergoing day care surgery. Method: 60 premedicated children between 1–12 years of age of ASA grade I or II posted for day care procedures were included in the study and received either induction with sevoflurane 7% by face mask and maintained with a 50% oxygen and 50% nitrous oxide mixture followed by 1.6% sevoflurane or induction with 3 mg/kg propofol IV followed by infusion of 170μg/kg/min with LMA. Demographic data, induction time, number of attempts, LMA insertion, removal and recovery times, haemodynamic parameters, complications, Modified Aldrete score were recorded. Results: Demographic data and induction time were comparable for both the groups. LMA insertion was successful at the first attempt in 83.3% with sevoflurane and 96.7% with propofol. LMA insertion, removal and recovery times were significantly shorter in the sevoflurane group (106.2±17.68 seconds, 2.41±0.39 minutes, 5.54±0.66 minutes respectively) than in the propofol group (122±13.32seconds, 5.24±0.23minutes,11.83±2.63 minutes respectively) (P<0.05). Modified Aldrete score were significantly higher in Sevoflurane group (8.50) than in Propofol (5.96) at 5 minutes (P<0.05) and similar at 10 and 15 minutes. Haemodynamics were similar in both groups and perioperative complications were comparable. Conclusions: Sevoflurane provided shorter LMA insertion, removal and recovery times than IV propofol in children undergoing day care surgeries with similar perioperative complications.