A COMPARATIVE STUDY BETWEEN EPIDURAL ROPIVACAINE AND EPIDURAL ROPIVACAINE WITH DEXMEDETOMIDINE IN PATIENTS UNDERGOING LOWER LIMB SURGERIES

Suneeta Dutta; Vilas Gajbhiye; DEBA GOPAL PATHAK

Volume : VIII, Issue : III, March - 2019

A COMPARATIVE STUDY BETWEEN EPIDURAL ROPIVACAINE AND EPIDURAL ROPIVACAINE WITH DEXMEDETOMIDINE IN PATIENTS UNDERGOING LOWER LIMB SURGERIES

Suneeta Dutta, Vilas Gajbhiye, Deba Gopal Pathak

Abstract :

OBJECTIVE: To study the synergistic effect of adding dexmedetomidine to ropivacaine 0.75% in epidural anaesthesia for lower limb surgeries. MATERIALS AND METHODS: 100 patients of American Society of Anaesthesiologist Grade I and II in age group of 20–60 years of either sex under going lower limb surgeries were included .They were assigned to two groups: Group A (n = 50), 18ml of 0.75% ropivacaine plus 2ml distill water. Dexmedetomidine Group B(n = 50), 18ml of 0.75% ropivacaine plus 1 mcg.Kg–1of dexmedetomidine diluted upto 2ml with distill water. Onset of sensory and motor block, duration of sensory and motor block, intensity of motor block, maximal dermatomal level of analgesia and hemodynamic parameters were studied. RESULTS: Time for onset of sensory analgesia is 9. 06 ±1.16 mins in group A and 5.14 ±1.24 mins in group B which is highly significant (p<0.0001),Onset of motor analgesia 15.51 ± 1.78 min in group A and 8.36 ± 1.74 mins in group B. which is highly significant P < 0.0001. Significant difference was observed relation to duration of sensory block (216.61 ± 24.09 min Group A and 376.93±35.56 min Group B [P < 0.0001]), duration of motor block (151.51 ± 11.18 min Group A and 201.16 ±6.25 min Group B [P< 0.0001]), and produce more intense motor block (p<0.001).There was no difference in the maximal dermatomal level of analgesia. CONCLUSION: Epidural Dexmedetomidine as an adjuvant to Ropivacaine is associated with prolonged sensory and motor block, hemodynamic stability, prolonged postoperative analgesia and when compared to plain Ropivacaine.