A comparison of intravenous Fentanyl and intervenous Lignocaine for attenuation of cardio-vascular responses to Laryngoscopy and Endotracheal intubation in routine elective cases

Volume : VII, Issue : VIII, August - 2018

Dr Chatterjee Tarit

Background :The study was carried out to compare the efficacy of Fentanyl and Lignocaine

on cardio–vascular responses to endotracheal intubation.

Method : Hundred ASA I & II were divided equally into groups A and B. Induction of

anaesthesia and intubation was performed with Propofol 2 – 2.2mg per kg and suxamethonium

1.5 mg per kg.Group A received Fentanyl 6 microgram / per kg 5 mins before induction and

Group B received Lignocaine 1.5 microgram /per kg, 90 secs before Laryngoscopy.

Measurements including heart rate; systolic, diastolic, mean blood pressure were noted in

each group before induction and 3 mins after intubation and were tabulated.

Results : After intubation incidents of tachycardia, rise in blood pressure were statistically

significantly high in Lignocaine group than in Fentanyl group.

Conclusion : Attenuation of cardiovascular response is seen in both groups. Of the two groups

Fentanyl is more effective.