A PROSPECTIVE RANDOMISED STUDY ON COMPARISON OF INDUCTION AND RECOVERY CHARACTERISTICS OF PROPOFOL AND THIOPENTONE FOR SHORT DURATION ENT SURGICAL PROCEDURES IN CHILDREN OF AGE GROUP 6 - 10 YEARS.

Dr.S.A.Namasivayam; Dr.N.Basker; Dr.G.K.Kumar; Dr.L.Parthasarathy

Volume : VII, Issue : XII, December - 2018

A PROSPECTIVE RANDOMISED STUDY ON COMPARISON OF INDUCTION AND RECOVERY CHARACTERISTICS OF PROPOFOL AND THIOPENTONE FOR SHORT DURATION ENT SURGICAL PROCEDURES IN CHILDREN OF AGE GROUP 6 - 10 YEARS.

Dr. S. A. Namasivayam, Dr. N. Basker, Dr. G. K. Kumar, Dr. L. Parthasarathy

Abstract :

Background and Aim : The aim of the study was to compare the induction and recovery characteristics of Thiopentone and Propofol in premedicated children in respect to

1.Smoothness of induction.

2.Hemodynamic changes during induction.

3.Recovery characteristics of the two drugs.

Materials and Methodology :In this prospective randomised study 50 paediatric patients in age group of 6 – 10 years belonging to ASA I and II scheduled to undergo elective tonsillectomy and adenoidectomy under general anaesthesia were included.The patients were randomly allocated to two groups as Group P and Group T of twenty five each.Group P received propofol and Group T received thiopentone as inducing agent.Induction time,Incidence of Pain during injection,Induction time,apnea seconds,Excitatory effects during induction,Hemodynamic variabilities,Quality of recovery were noted and compared.

Results :The total incidence of pain during injection in propofol group (20%) was greater than in the thiopentone group (8%).The mean induction time in propofol group was 31.84 seconds and in the thiopentone group was 30.36 seconds and the difference is not statisticallly significant.Mean duration of apnea following induction in propofol group is 11.96 seconds while in thiopentone group was 11.64 %.Apnea over 30 seconds in propofol group was 8% and in the thiopentone group was 16% which is staistically significant.Total incidence o excitatory effects in propofol group was 32% while in thiopentone group was 20% which is statistically significant.The fall in systolic,diastolic,mean arterialpressure is statistically significant in propofol group compared to thiopentone group.The mean decrease in pulse rate also significant in propofol group compared to thiopentone group.Post operative agitattion,unco–operativeness and crying found to be more in thiopentone group compared to propofol group which is statistically significant.

Conclusion :The results of the study indicate that Propofol is safe and more effective anaessthetic agent compared to Thiopentone for short duration ENT procedures in fit children.