A Review on Glucose Tolerance Test as a Laboratory Tool in clinical and Laboratory Medicine

P.V. Ram Prasad; E. Prabhakar Reddy

Volume : VIII, Issue : IX, September - 2019

A Review on Glucose Tolerance Test as a Laboratory Tool in clinical and Laboratory Medicine

P. V. Ram Prasad, E. Prabhakar Reddy

Abstract :

Diabetes mellitus (DM) and its related complications, such as cardiovascular diseases, acquired blindness, chronic kidney disease, and non–traumatic limb loss, are major causes of morbidity and mortality in India. It has already been proven by multiple studies that strict blood glucose control is essential to prevent chronic complications of diabetes. Tight glycemic control through active intervention soon after diagnosis has been shown to prevent microvascular complications as well as macrovascular complications, denoting that early and active treatment is important. In addition, identifying patients with impaired glucose tolerance (IGT) or impaired fasting glucose (IFG). The currently used methods to identify diabetes include the fasting plasma glucose (FPG) level test, oral glucose tolerance test (OGTT), and glycosylated hemoglobin (HbA1c) level test. we conclude that the 2–hour glucose concentration criterion on an oral glucose tolerance test for the diagnosis of diabetes should be raised from 11.1 mmol/L (200 mg/dL) to $ 13.3 mmol/L (240 mg/dL) to remain faithful to the concept that diagnostic concentrations of glucose should predict the subsequent development of specific diabetic complications.