A STUDY OF CLINICAL PROFILE OF TUBERCULOSIS IN PATIENTS WITH HIV INFECTION/AIDS

Dr. Rana R.K.Singh; Dr.(Prof.) M.P.Singh

Volume : VIII, Issue : II, February - 2019

A STUDY OF CLINICAL PROFILE OF TUBERCULOSIS IN PATIENTS WITH HIV INFECTION/AIDS

Dr. Rana R. K. Singh, Dr. Prof. M. P. Singh

Abstract :

Tuberculosis (TB) and HIV co–infections place an immense burden on health care systems and pose particular diagnostic and therapeutic challenges. Infection with HIV is the most powerful known risk factor predisposing for Mycobacterium tuberculosis infection and progression to active disease, which increases the risk of latent TB reactivation 20–fold. TB is also the most common cause of AIDS–related death. A study was carried out to study the clinical, bacteriological and radiological features of HIV/TB patients .Over the period of two years,a total of 100 tuberculosis patients were suspected to have HIV/AIDS co–infection, and upon testing, 16 patients were found to be HIV seropositive..Most of the study patients were manual labourers followed by truck drivers. Heterosexual promiscuous behaviour was found to be a major risk factor in HIV transmission. The most common symptom in these patients was cough and expectoration, followed by fever and weight loss. Acid–fast bacilli (AFB) smear positivity was found in 18.75% patients. On chest skiagram, infiltrative lesions were commonly seen in 56.25% patients. Extra–pulmonary tubercular manifestations were seen in 43.75% of HIV/TB cases