A STUDY OF COGNITIVE FUNCTION IN DIFFERENT STAGES OF CHRONIC KIDNEY DISEASE

Dr. C. Aravind Sriram; Dr. B. Hari Krishna; Dr. T. Prathyusha; Dr. M Ramesh

Volume : VII, Issue : I, January - 2018

A STUDY OF COGNITIVE FUNCTION IN DIFFERENT STAGES OF CHRONIC KIDNEY DISEASE

Dr. C. Aravind Sriram, Dr. B. Hari Krishna, Dr. T. Prathyusha, Dr. M Ramesh

Abstract :

Background: Chronic kidney disease (CKD) is a growing public health problem. The incidence of kidney failure is rising in all age groups but particularly in older adults. Individuals in all stages of CKD are at higher risk for development of cognitive impairment and this may be a major determinant in their quality of life. Furthermore, cognitive impairment is associated with an increased risk of death in dialysis patients. Main objective is to study cognitive function in various stages of CKD.

Methods: In our study 200 CKD patients were taken, who are admitted in DR PSIMS &RF in last 1 year and they were diagnosed and classified into different stages of CKD based on EGFR by MDRD formula. cognitive function assessment done by using MMSE(mini mental state examination)scoring system.

Results: Out of 200 CKD patients 38 are CKD1 , 45 are CKD II, 35 are CKD III, 33 patients are CKD IV, 28 are CKD V, 34 belongs to MHD(maintenance on haemodialysis) group. Significant P value(<0.001) observed in CKD V and MHD group patients

Conclusions: The present study emphasizes that no significant cognitive impairment in CKD stage 1– 4, but some significant cognitive impairment in CKD stage V and MHD group