Volume : VIII, Issue : VIII, August - 2019

A STUDY OF EXPRESSION OF THYROID TRANSCRIPTION FACTOR (TTF-1) IN ENDOMETRIAL ADENOCARCINOMA OF UTERINE CORPUS

Dr. M. Brinda, Dr. S. Maheswari, Dr. Sasikumar Sambasivam

Abstract :

Among females endometrial carcinoma is the most frequent malignancy worldwide. Thyroid transcription factor has been regarded as a specific and sensitive marker for tumors arising in thyroid and lung. But some studies state that TTF 1 marker is also expressed in endometrial adenocarcinoma. The aim of this study is to probe the incidence of Thyroid transcription factor expression in primary uterine endometrial adenocarcinoma and to correlate the percentage of expression of TTF–1 with the grade of endometrial adenocarcinoma. TTF 1 immunohistochemistry was done for 50 cases out of which two cases of moderately differentiated endometrioid adenocarcinomas and 1 case of poorly differentiated endometrioid adenocarcinoma showed focal and diffuse positivity respectively .

Keywords :

Endometrial carcinoma   TTF 1  

Article: Download PDF    DOI : https://www.doi.org/10.36106/paripex  

Cite This Article:

A STUDY OF EXPRESSION OF THYROID TRANSCRIPTION FACTOR (TTF-1) IN ENDOMETRIAL ADENOCARCINOMA OF UTERINE CORPUS, Dr.M.Brinda, Dr.S.Maheswari, Dr. Sasikumar Sambasivam PARIPEX‾INDIAN JOURNAL OF RESEARCH : Volume-8 | Issue-8 | August-2019


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