A study of whole versus split dose preparation with Exelyte solution prior to colonoscopy.

Dr. Samadhan Narsing Kshirsagar; Dr. Nikhil Phadke

Volume : VIII, Issue : IX, September - 2019

A study of whole versus split dose preparation with Exelyte solution prior to colonoscopy.

Dr. Samadhan Narsing Kshirsagar, Dr. Nikhil Phadke

Abstract :

Introduction: Colonoscopy is the current standard method for evaluation of the colon. Diagnostic accuracy and therapeutic safety of colonoscopy depends on the quality of the colonic cleansing or preparation. To assess the Cleanliness quality score of split–dose preparation and one–time preparation, assess the clarity of mucosa and compare cleanliness quality scores in split–dose vs one–time preparation. Material and Method: It is a prospective study on patients coming for Colonoscopic evaluation at department of general Surgery of MIMER Medical College & Hospital Talegaon. All the details of the patients were collected according to pre–designed proforma. Total of 50 patients aged between 18–70years were included in study after obtaining informed consent. 50 patients were divided into 2 groups as; Group A: 25 patients with whole dose one–time preparation; Group B: 25 patients with split–dose preparation. Result: There were total 14 females and 36 males in study. The Mean cleanliness quality score was found to be significantly lower in the Group B (3.20 ± 1.11) patients compared to patients in Group A (1.44 ± 0.58). Split preparation had a better efficacy compared to the one–time bowel preparation. There is a significant strength of association of cleanliness of bowel and the type of preparation done in patients, Group B showed to be better. Discussion and Conclusion: There is significant association of bowel cleanliness grade and type of bowel preparation performed in patients. Split–dose bowel preparation is significantly correlated strongly with cleanliness and visibility during the colonoscopy compared with the one–time–bowel preparation. The grade scores are significantly better in the split–dose preparation than the conventional one–time bowel preparation. Split evening–morning dose for colonoscopy preparation is found to be superior to the single conventional one–time bowel preparation with a better colon cleansing and visibility on colonoscopy. The Exelyte solution for the colon preparation is found to be effective, better tolerability, and acceptable with low cost of price benefit.