A STUDY ON COMPARING LIVER FUNCTION TEST AND C-REACTIVE PROTEIN IN CHILDREN WITH HAND FOOT MOUTH DISEASE

Dr.Princy Joseph

Volume : VIII, Issue : I, January - 2019

A STUDY ON COMPARING LIVER FUNCTION TEST AND C-REACTIVE PROTEIN IN CHILDREN WITH HAND FOOT MOUTH DISEASE

Dr. Princy Joseph

Abstract :

Introduction: Hand–foot–mouth disease (HFMD) is a common paediatric disease responsible for the development of erythematous papulovesicular rashes on the hand, foot, and mouth. Severe complications of HFMD include myocarditis, pulmonary oedema, aseptic meningoencephalitis, and even death. Therefore, early diagnosis of HFMD is of particular importance. Objectives of this study: To compare the values of liver function test and CRP in mild and severe cases of HFMD. Materials and methods: Retrospective hospital based study of 100 patients between August 2016 to July 2018 who were classified into mild and severe HFMD cases. Lab investigations included ALT,AST, CRP. Clinical and laboratory parameters in the two group of HFMD were compared in the study . Results: Study group included 100 cases of HFMD of which was 58% Severe cases and 42% Mild cases of HFMD. Commonest presenting symptom was erythematous papulo vesicular rashes on the hand, foot, and mouth. Severe HFMD is characterized by rapid disease progression, continuous hyperpyrexia, significant increase in the peripheral white blood cell level and poor peripheral circulation. Lab parameters: Patients in the severe HFMD group showed significantly higher levels of ALT, AST and CRP compared to those in the mild HFMD group . Conclusion: CRP and liver function play a major role in the diagnosis of severity of HFMD at an earlier stage.