A STUDY ON EVALUATION OF THYROID FUNCTION TEST IN PATIENTS WITH CHRONIC LIVER DISEASE

DR INDU KIRAN; Dr. GANESH PRASAD

Volume : IX, Issue : II, February - 2020

A STUDY ON EVALUATION OF THYROID FUNCTION TEST IN PATIENTS WITH CHRONIC LIVER DISEASE

Dr Indu Kiran, Dr. Ganesh Prasad

Abstract :

INTRODUCTION: Liver plays an important role in metabolism and modification of several hormones, including thyroid hormones. Therefore, the circulating thyroid hormone concentrations are affected by hepatic disorders. The most consistent thyroid hormone profile in patients with CLD are low total and free T3 and an elevated rT3, changes similar to sick euthyroid syndrome. AIMS : To find out relation of thyroid hormone level with severity of chronic liver disease. METHOD : A cross sectional study was conducted to evaluate thyroid function in 100 patients of chronic liver disease. RESULT : Serum fT3 & fT4 level fall significantly along with progression of liver disease, values were inversely related with disease severity. However, TSH value was not significantly changed with severity of liver disease. CONCLUSION: Since, there is significant inverse correlation between serum level of T3, FT3, and FT4 with severity of cirrhosis, these parameters can be used as markers to indicate the severity of cirrhosis.