A STUDY TO EVALUATE THE POSTOPERATIVE ANALGESIC EFFICACY OF DEXMEDETOMIDINE ADDED TO INTRATHECAL ROPIVACAINE IN LOWER LIMB ORTHOPAEDIC SURGERIES

Dr.B.MOHAMMED SAMEER; Dr.S.LEO

Volume : VII, Issue : V, May - 2018

A STUDY TO EVALUATE THE POSTOPERATIVE ANALGESIC EFFICACY OF DEXMEDETOMIDINE ADDED TO INTRATHECAL ROPIVACAINE IN LOWER LIMB ORTHOPAEDIC SURGERIES

Dr. B. Mohammed Sameer, Dr. S. Leo

Abstract :

Aim

This study was conducted to evaluate the hemodynamic effects and postoperative analgesic efficacy of dexmedetomidine added to intrathecalropivacaine in lower limb orthopaedic surgeries.

Materials and methods

Fifty patients undergoing elective lower limb orthopaedic surgeries under spinal anaesthesia were randomly allocated into two groups of 25 each.Group R received3ml of 0.75% Ropivacaine plus 0.5ml of normal saline intrathecally.Group D received 3ml of 0.75% Ropivacaineplus 5µgm of Dexmedetomidine in 0.5 ml of normal saline intrathecally.

Time of onset, Highest level of sensory block, time taken to reach the highest level, time to two segment regression, time to sensory regression to S2 dermatome, adverse effects, VAS and sedation scores in the post operativeperiod were recorded.

Results

The time of onset of sensory block was faster in group D ( 3.52 ± 1.66) when compared with group R (5.04 ± 1.43). In group D, the time to two segment regression was prolonged (116.4 ±14.7) when compared with group R (78.8± 7.8) and was statistically significant. Time to sensory regression to S2 dermatome was 451.6±29.6minutes in group D and 252.8±16.5 minutesin group R. Itwas statistically significant.Time of rescue analgesic was 28.7 min in Group D and 12.9 min in Group R (P<0.05).Post op dose of tramadol was less in Group D compared to Group R.

Conclusion:

Dexmedetomidine 5 μg as an adjuvant to intrathecalropivacaine, produces faster onset and longer duration of sensory blockade, with stable hemodynamicparameters and lesser adverse effects.