Acute poisoning at the critical care and toxicology unit of the Joseph Ravoahangy Andrianavalona teaching hospital, Antananarivo, Madagascar

RAZAFINDRAIBE Faneva Angelo Parfait; RAKOTOMAVO Falihery Albertin; RAMAROLAHY Rija Niaina; RAKOTOARISON Ratsaraharimanana Catherine Nicole; RAVELOSON Nasolotsiry Enintsoa

Volume : IX, Issue : I, January - 2020

Acute poisoning at the critical care and toxicology unit of the Joseph Ravoahangy Andrianavalona teaching hospital, Antananarivo, Madagascar

Razafindraibe Faneva Angelo Parfait, Rakotomavo Falihery Albertin, Ramarolahy Rija Niaina, Rakotoarison Ratsaraharimanana Catherine Nicole, Raveloson Nasolotsiry Enintsoa

Abstract :

Background : Acute poisoning (APP) constitutes a serious problem of public health worldwide. Our aims are to determinate the clinical characteristics and the outcome of these intoxication and to identify the factors which are associated to the mortality. Methodology : A 12 month retrospective and cross–sectional study was carried out at the critical care and toxicology unit of the Joseph Ravoahangy Andrianavalona teaching hospital, Antananarivo, Madagascar, from January to December 2013. Results: Of the 485 cases of intoxication identified, 56.1% were male. The average age of the patients was 27.13+/–14.28 years. Agricultural and industrial products were the most reported poisoning agents (33.5%). The muscarinic syndrome was the most toxic syndrome observed (24.7%). Hypoglycaemia (9.3%) was the most frequent biological abnormalities. The mortality rate was 16.7%. The factors associated with mortality were the male gender, the advanced age, the existence of comorbidities, the suicide, the existence of co–intoxication and radiologic abnormalities (p<0.05). Conclusion: The admission for acute poisoning is frequent at our unit. The mortality remains high. Multiple interventions are needed to reduce the prevalence of intoxication