AN EVALUATION OF THE EFFICACY OF ADDING CLONIDINE TO BUPIVACAINE IN INFRA-CLAVICULAR APPROACH OF BRACHIALPLEXUS BLOCK

Dr. B. Mohamed Sameer; Dr. J. Jayamurugavel

Volume : VII, Issue : III, March - 2018

AN EVALUATION OF THE EFFICACY OF ADDING CLONIDINE TO BUPIVACAINE IN INFRA-CLAVICULAR APPROACH OF BRACHIALPLEXUS BLOCK

Dr. B. Mohamed Sameer, Dr. J. Jayamurugavel

Abstract :

AIM: To evaluate the effects of adding alpha adrenergic agonist Clonidine as an adjuvant to bupivacaine in blocking achial plexus by infraclavicular approach. Materials and Methods:60 ASA I and II patients undergoing upper limb surgeries under infra clavicular achial plexus block .They were randomly divided into two groups namely Group B, Group BC. Group B (Bupivacaine + normal saline) –30 patients received 38ml of 0.25% Bupivacaine and 2ml of normal saline. Group BC ( Bupivacaine + clonidine) –30 patients received 38ml 0f 0.25% Bupivacaine, 150µg (1 ml) of clonidine and 1ml of normal saline .The onset and duration of sensory and motor block ,changes in mean blood pressure and mean pulse rate was assessed. Observation and Results: The onset time of sensory block was less in group BC( 14.76min) as compared to group B (17.70min), which was found to be just significant (p <0.05). The onset time of motor block is less in group BC (17.50mins) as compared to group B (22.03 mins). The difference in duration of sensory block between group BC (898 min) and group B (243 min) was found to be statistically significant (p<0.05). The difference in duration of motor block between group BC (820.66 min) and group B (196.16 min) was found to be significant statistically. The mean blood pressure in both groups was found to be comparable (p>0.05). Results: The mean time of onset of sensory and motor block was faster in Group BC (14.76 ± 1.10 min, 17.50±0.86 min ) than Group B (17.70±1.08 min, 22.03±1.49min) respectively. Conclusion: Addition of 150 mcg of clonidine to 0.25% bupivacaine accelerates the onset of motor and sensory block, prolongs analgesia without any adverse effect in achial plexus block for upper limb surgeries.