ANTIMICROBIAL SUSCEPTIBILITY OF MYCOPLASMA AND UREAPLASMA STRAINS FROM GENITAL TRACT

Roxana Filip; Irina Larisa Iancu; Laurian Lucian Francu

Volume : VII, Issue : I, January - 2018

ANTIMICROBIAL SUSCEPTIBILITY OF MYCOPLASMA AND UREAPLASMA STRAINS FROM GENITAL TRACT

Roxana Filip, Irina Larisa Iancu, Laurian Lucian Francu

Abstract :

The aim of this study was to determine the sensitivity pattern of Mycoplasma hominis and Ureaplasma urealyticum strains from the genital tract among male and female asymptomatic patients. The study series included 99 samples, isolated between 2008–2010 in outpatient clinic, from which 39 positive, 34 U. urealyticum and 5 M. hominis, respectively. Samples examined were urethral endocervical swab. Detection, quantification and antimicrobial susceptibility testing were performed by Mycoplasma IST–2 test (BioMerieux, Marcy L’Etoile) against nine antimicrobial agents supplied in the kit. U. urealyticum was resistant to Ofloxacin (73.5%) and Ciprofloxacin (85.2%) and M. hominis to: Erythromycin, Clarithromycin, Azithromycin, Ofloxacin, Ciprofloxacin (100%). Significantly more M. hominis were resistant to Tetracycline (60%) than Ureaplasma urealyticum (11.7%). Doxycycline is the drug of first choice in the treatment of U. urealyticum infections, and may be used for co infection with M. hominis; this fact correlates with data from literature, in which this agent is used in the empirical therapy.