ANTIRETROVIRAL THERAPY AND PREGNANCY OUTCOME IN HIV INFECTED WOMEN

Dr. Gopal Singh Dhaka; Dr. Purnima Pachori; Dr. Suchitra Narayan

Volume : IX, Issue : VII, July - 2020

ANTIRETROVIRAL THERAPY AND PREGNANCY OUTCOME IN HIV INFECTED WOMEN

Dr. Gopal Singh Dhaka, Dr. Purnima Pachori, Dr. Suchitra Narayan

Abstract :

Objectives: There is conflicting data on the effect of HIV infection as well as antiretroviral therapy (ART) on pregnancy outcome. The objectives of this study were to evaluate the effect of HAART on pregnancy in HIV–infected women. Methods: This is a prospective case record analysis of 100 HIV–infected women delivering between March 2018 to Oct 2019, in RMC, Ajmer. The pregnancy outcome in HIV–infected women who received ART for prevention of mother to child transmission as per protocol which varied during the period of study. Effect of use of ART and latest CD4 count on preterm birth (PTB) and intrauterine growth restriction (IUGR) and pre–eclampsia were analyzed. Results: HIV–infected women were more likely to have Pre–eclampsia, PTB and IUGR (7%, 14%, 13%). This did not reach statistical significance (p>0.05). Neonatal intensive care unit admissions were also significantly higher in infants born to HIV–infected women. HIV–infected women on ART had decreased incidence of Pre–eclampsia, PTB and IUGR. Conclusion: Good antenatal care and multidisciplinary team approach can optimize pregnancy outcomes in HIV–infected women.