Assessment of machine related factors affecting platelet yield in single donor platelets

Sachdeva Puneet; Dr Gagandeep Kaur; Basu Sabita; Tahlan Anita

Volume : VII, Issue : III, March - 2018

Assessment of machine related factors affecting platelet yield in single donor platelets

Sachdeva Puneet, Dr Gagandeep Kaur, Basu Sabita, Tahlan Anita

Abstract :

Background: The quality of single donor platelets (SDP) in terms of yield influences the platelet recovery in the recipient. Various machine/procedure related factors such as volume of whole blood processed and time taken for the procedure may affect platelet yield.

Aim: The aim of present study was to assess the effect of various machine/procedure related factors on platelet yield.

Materials and methods: A total of 171 plateletpheresis procedures performed using continuous flow cell separator (Amicus Automated Blood Collection System version 2.52/3.1) were evaluated for platelet yield.

Results: The mean platelet yield was 3.8 + 1.65 X 10¹¹ /unit. Platelet yield correlated positively with total whole blood processed (r=0.503; p < 0.001), time taken for the procedure (r = 0.284; p < 0.001) and ACD used (r = 0.519; p < 0.001). No correlation was observed between MIR and platelet yield (r = 0.101; p = 0.248).

Conclusion: Appropriate importance should be given to various machine/procedure related factors during the plateletpheresis procedure to have improved product quality.