BETA-GLUCAN AND FOS ADDED BARLEY SLIMS IMPROVES GLYCEMIA, GUT HEALTH AND INFLAMMATORY STATUS OF TYPE 2 DIABETES MELLITUS INDIVIDUALS RESIDING IN URBAN VADODARA

Mini Sheth; Meghana Patel

Volume : VIII, Issue : IX, September - 2019

BETA-GLUCAN AND FOS ADDED BARLEY SLIMS IMPROVES GLYCEMIA, GUT HEALTH AND INFLAMMATORY STATUS OF TYPE 2 DIABETES MELLITUS INDIVIDUALS RESIDING IN URBAN VADODARA

Mini Sheth, Meghana Patel

Abstract :

Aim: To study the impact of barley slims supplementation on glycemic, inflammatory status and gut health of type 2 DM subjects Method: A randomized, placebo controlled trial was undertaken wherein 47 adult type 2 DM subjects were selected from private clinics of urban Vadodara. The placebo and experimental group were supplemented wheat slims and barley slims (6 grams beta glucan powder and 2 ml of Fructooligosaccharides) respectively for a period of 45 days. Results: At baseline, a strong correlation was observed between the beneficial microflora and glycemic parameters. Barley slims supplementation showed significant reduction in weight, BMI, SBP, FBS, ABG, HbA1c and fructosamine by 1.1%, 0.7%, 3.5%,14%, 4.3%, 3.8% and 3% respectively. hs–CRP and homocysteine levels reduced non–significantly by 8% and 9% respectively. Fecal log counts of Lactobacillus and Bifidobacterium increased significantly by15%and 11.2% and E.coli was reduced significantly by 22% (p<0.001). Conclusion: Intake of barley slims (6 gram of beta glucan and 2 ml of Fructooligosaccharides)in the diets of type 2 diabetic patients improves glycemia, gut health and reduces inflammation.