Chronological approach of sequential drug utilisation in chronic eczema: data analysis

Dr. Sudhakar M Parhate; Dr.Renuka S Harwani; Dr. Dheeraj Jeswani

Volume : VIII, Issue : VII, July - 2019

Chronological approach of sequential drug utilisation in chronic eczema: data analysis

Dr. Sudhakar M Parhate, Dr. Renuka S Harwani, Dr. Dheeraj Jeswani

Abstract :

Pharmacovigilance survey for prescriptions of chronic eczema revealed prescription of irrational cluster of drugs which at the outset seemed to not offer relief. Hence we assessed the therapeutic efficacy of standard drugs scientifically with reference to the pathology and mechanism of drug action. Data collected of 320 adult men with chronic eczema (< 5 yr. duration) between age 25–44 yr. and analysed for sequential efficacy. Patients were treated in two stages over 16 weeks. The initial stage of topical antimicrobial application (gentian violet, mercurochrome, povidone–iodine) was done every fourth day. Wound healing was recorded weekly. From first week onwards, the healing of small size and superficial wounds was observed and gradually the other wounds healed over 16 weeks. In the second stage, those showing healing were prescribed ointment clobetasol and salicylic acid. Within subsequent one to two months there was satisfactory post–healing repair without any skin thickening and pigmentation.