Clinical and metabolic profile of polycystic ovarian syndrome in eastern indian population.

Somnath Singh Raghuvanshi; Anirban Sinha; Animesh Maiti; A K Basu

Volume : VIII, Issue : XII, December - 2019

Clinical and metabolic profile of polycystic ovarian syndrome in eastern indian population.

Somnath Singh Raghuvanshi, Anirban Sinha, Animesh Maiti, A K Basu

Abstract :

Polycystic ovarian syndrome (PCOS) is most common endocrine abnormality in women of reproductive age. Several studies of diverse populations have estimated its prevalence at 6% – 10%.Most patients with PCOS have metabolic abnormalities such as insulin resistance with compensatory hyperinsulinemia, obesity, and dyslipidemia. All of these metabolic features may play a role in the development of glucose intolerance or type 2 diabetes mellitus and hypertension, thereby increasing cardiovascular diseases. Aim : To evaluate the prevalence of metabolic & clinical manifestation of poly cystic ovarian syndrome in eastern Indian population. Material and method: This was a single centre observational Cross–sectional study carried out in the department of Endocrinology and metabolism, Medical College, Kolkata from march 2017 to January 2019.Results: The mean BMI were 24.73 and 22.25 kg/m2 & there is significant difference in the BMI. There was significant difference in the Waist hip ratio among the case and the control. The mean systolic and mean diastolic blood pressure were significantly higher among the cases .The most of the cases had mild Hirsutism with a median score of 8. Acne were significantly higher in the PCOS group as compare to control group (<0.001).The grade 1 was the most common pattern & The cases have significantly less number of cycle per year (p 0.001) and the 83.33% cases and 14.49% control had oligomenorrhea.