CLINICAL EQUIVALENCE OF HEPARINIZED ARTERIAL PLASMA TO VENOUS SERUM SAMPLES FOR PHOSPHATE MEASUREMENT IN CRITICAL PATIENTS AT MOI TEACHING AND REFERRAL HOSPITAL.

DOMINIC ALWALA

Volume : VIII, Issue : VII, July - 2019

CLINICAL EQUIVALENCE OF HEPARINIZED ARTERIAL PLASMA TO VENOUS SERUM SAMPLES FOR PHOSPHATE MEASUREMENT IN CRITICAL PATIENTS AT MOI TEACHING AND REFERRAL HOSPITAL.

Dominic Alwala

Abstract :

Electrolytes excluding phosphate are measured as part of tests done during blood gas analysis (BGA) using arterial blood in Intensive Care Unit (ICU) patients. Phosphate is measured from a venous serum sample since it cannot be measured during BGA. Plasma obtained from sodium–heparin anticoagulant is yet to be used as a sample of choice for measuring phosphate since it is not clear whether there is clinical equivalence between concentrations obtained from venous serum and arterial plasma. It is clinically important that those measurements should give equivalent results and confirm the closeness to the absolute value. This study assessed the equivalence of arterial and venous blood phosphate concentration. Mean difference between phosphate concentration in plasma and serum was 0.14(t=1.18) p=0.24. Phosphate correlation between plasma and serum was r=0.99 [P = 0.00 (< 0.05)]. The study indicated clinical equivalence between phosphate concentration in arterial blood plasma and venous blood serum.