Clinical, Laboratory, and Management Profile in Patients of Liver Abscess from Southern Odisha.

Iswar Chandra Muduli; Subhashis Patra; Sworupa Nanda Mallick; V.Rajesh

Volume : VII, Issue : IX, September - 2018

Clinical, Laboratory, and Management Profile in Patients of Liver Abscess from Southern Odisha.

Iswar Chandra Muduli, Subhashis Patra, Sworupa Nanda Mallick, V. Rajesh

Abstract :

To describe the clinical profile, microbiological aetiologies, and management outcomes in patients with liver abscess.Across–sectional study was conductedfrom June 2016 to May 2018 at the Department of General Surgery, MKCG Medical College, Berhampur.History,examination & laboratory investigationswere recorded.Ultrasound guided aspirationwas done and samples were investigated. Chi–square test and multivariate regression analysis were performed to test association.

Results. The mean age of patients was 42.13 years. Majority of them were from lower socioeconomic class (67.5%) and alcoholic(72%). The abscesses were predominantly in right lobe (71%) and solitary (65%). Etiology of abscess was 69% amoebic, 18%

pyogenic, 7.5%tubercular, 4%mixed, and 1.5%fungal. Percutaneous needle aspiration was done in 79%, pigtail drainage in 17%, andsurgical intervention for rupture in 4% patients.Mortality was 2.5%, all reported in surgical group. Solitary abscesses were amoebicand tubercular whereas multiple abscesses were pyogenic (𝑃 = 0.001). Right lobe was predominantly involved in amoebic andpyogenic abscesses while in tubercular abscesses left lobe involvement was predominant (𝑃 = 0.001). Conclusions.The commonestpresentation was young male, alcoholic of low socioeconomic class having right lobe solitary amoebic liver abscess. Appropriateuse of minimally invasive drainage techniques reduces mortality