Comparative Analysis of Safety, Efficacy and Fetomaternal Outcome of Induction of Labour with Mifepristone versus Intracervical Dinoprostone Gel.

Dr. Raji Chinniah; Dr. Saranya Arumugam

Volume : VIII, Issue : III, March - 2019

Comparative Analysis of Safety, Efficacy and Fetomaternal Outcome of Induction of Labour with Mifepristone versus Intracervical Dinoprostone Gel.

Dr. Raji Chinniah, Dr. Saranya Arumugam

Abstract :

Objective: This study compares the efficacy of Mifepristone and Dinoprostone gel as a cervical ripening agent for induction of labour and to assess fetomaternal outcome. Methods: It is a single blind prospective randomized comparative study.200 women with 41 weeks of gestation were selected. 100 women received 200mg oral mifepristone and 100 women received 0.5mg dinoprostone gel intracervically . Pre induction and Post induction Bishop’s score 6 hours after dinoprostone and 24 hours after mifepristone or with onset of labour, whichever was earlier was assessed. When score was favourable oxytocin augmentation was started. Maternal and Neonatal outcome were observed Results: Vaginal delivery occurred in 82% with Mifepristone and 73% with Dinoprostone. After induction with Mifepristone 71% women had cervical ripening as compared to 62% with Dinoprostone. NICU admissions were low with mifepristone. Conclusion: Favourable bishops score occurred in mifepristone group