Comparative efficacy, tolerability and safety of tramadol and NSAIDs in postoperative pain, an observational study.

Dr. Sudhakar M Parhate; Dr.Renuka S Harwani; Dr. Mayank S Jeswani

Volume : VIII, Issue : VI, June - 2019

Comparative efficacy, tolerability and safety of tramadol and NSAIDs in postoperative pain, an observational study.

Dr. Sudhakar M Parhate, Dr. Renuka S Harwani, Dr. Mayank S Jeswani

Abstract :

Adult male patients of age 25–55 years, undergone surgery for hydrocele,inguinal hernia and haemorrhoids (n=594) were enrolled for comparative analysis of efficacy and safety of tramadol and NSAID in postoperative period. The drugs prescribed were diclofenac, ibuprofen, indomethacin and tramadol. The analgesic effect reported from 3rd day onward (all drugs) in few and covered remaining patients up to day 5 by diclofenac, indomethacin; up to day 6 by ibuprofen, tramadol. Analgesic efficacy observed as: Indomethacin > Diclofenac > Ibuprofen > Tramadol. Adverse effects manifested as gastric (n=55) due to NSAID and neurological (n= 39) due to tramadol. All adverse effects were mild, well tolerated, required no discontinuation of treatment. Postoperative recovery was satisfactory.