Volume : IX, Issue : II, February - 2020

Comparative evaluation of diagnostic Markers in Myocardial Infarction

Hardi Prajapati, Meghna Patel

Abstract :

Background: Myocardial Infarction is the process of myocardial cell death due to ischemia or Imbalance between the supply and demand of oxygen within the coronary arteries. The study of cardiac markers like Troponin T, Troponin I, CK–MB and NT–Pro BNP are being used currently in the assessment of Myocardial Infarction. Methods: The study was conducted at cardiac center of Mahavir cardiac hospital , Surat. A total of 222 patients of suspected myocardial infarction presented within 12hrs of onset of symptoms were enrolled. They were diagnosed for MI using various Biochemical Markers like Troponin T, Troponin I, CK–MB, NT–Pro BNP and other radiology test like ECG, Echo and Angiography. The confirmation of event of MI was done by the respective physician by checking all the test result as well as clinical checkups. Result: We found 88.5% sensitivity and 64.7% specificity for Troponin T as compare to Troponin I(85.7% and 45.5%) , CPK–MB (64.3% and 37.5%) and NT–Pro BNP (66.7% and 54.7%). Conclusion: Troponin T offers higher sensitivity and specificity as compare to other markers for diagnosis of Myocardial Infarction and valuable tool for risk stratification in patient with acute chest pain.

Article: Download PDF    DOI : https://www.doi.org/10.36106/paripex  

Cite This Article:

COMPARATIVE EVALUATION OF DIAGNOSTIC MARKERS IN MYOCARDIAL INFARCTION, Hardi Prajapati, Meghna Patel PARIPEX-INDIAN JOURNAL OF RESEARCH : Volume-9 | Issue-2 | February-2020

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