COMPARISON OF PULMONARY FUNCTIONS AND DIFFUSION CAPACITY IN TYPE 2 DIABETES MELLITUS WITH OR WITHOUT COMPLICATIONS : A HOSPITAL BASED STUDY IN EASTERN INDIA.

Dr. Tanushree Mondal; Dr. Md. Salim Uz Zaman

Volume : VIII, Issue : XII, December - 2019

COMPARISON OF PULMONARY FUNCTIONS AND DIFFUSION CAPACITY IN TYPE 2 DIABETES MELLITUS WITH OR WITHOUT COMPLICATIONS : A HOSPITAL BASED STUDY IN EASTERN INDIA.

Dr. Tanushree Mondal, Dr. Md. Salim Uz Zaman

Abstract :

Background: Diabetes mellitus is a systemic disease that causes secondary metabolic changes involving kidney, eyes, nerve, heart and vasculature causing severe social burden. Considering large microvasculature and abundant connective tissues, pulmonary system is prone to be affected in diabetes. Aims and Objectives: To compare the parameters of Pulmonary functions and diffusion capacity in Type2 Diabetes with or without complications. Methods: A total of 60 T2DM patients with or without complications of age group 35–55years and 60 age and sex matched control were included after inclusion and exclusion criteria. All subjects were evaluated for PFT by RMS HELIOS 401 and Diffusion capacity (DLCO) by single eath technique– INSPIRE HD –PFT) and status of microangiopathies were evaluated by microalbuminuria for nephropathy, by clinical examination and autonomic studies for neuropathy and Ophthalmoscopy for retinopathy. p<0.05 was considered as significant. Results: There was significant(P=0.0001) reduction in FVC% in complicated T2DM and also reduction in diffusion capacity (DLCO% and DL/VA%) in Type2 diabetes cases having microangiopathic complications which is significantly (0.0001) comparable. Conclusion: There was significant impairment of Vital capacity and diffusion capacity of lung with restrictive pattern in Type2 diabetes with microangiopathic complications compared to T2DM without complications.