COMPARISON OF THE EFFECTS OF THREE DIFFERENT DOSES OF 0.5% BUPIVACAINE (7.5mg, 8.75mg & 10mg) IN WOMEN UNDERGOING ELECTIVE CAESAREAN SECTION UNDER SPINAL ANAESTHESIA.

Dr Chennagiri Gangappa Ravindra; Dr Shashank Maladkar; Dr Karthik Shivani Lokeshappa

Volume : VII, Issue : II, February - 2018

COMPARISON OF THE EFFECTS OF THREE DIFFERENT DOSES OF 0.5% BUPIVACAINE (7.5mg, 8.75mg & 10mg) IN WOMEN UNDERGOING ELECTIVE CAESAREAN SECTION UNDER SPINAL ANAESTHESIA.

Dr Chennagiri Gangappa Ravindra, Dr Shashank Maladkar, Dr Karthik Shivani Lokeshappa

Abstract :

BACKGROUND: Caesarean sections both for elective & emergency cases are most commonly done under spinal anaesthesia. For caesarean sections bupivacaine is the most preferred drug now a days. A number of studies have sought an optimal dose of bupivacaine, but produced dissimilar findings with doses ranging from 5 to 15 mg. MATERIAL & METHODS: 90 patients undergoing elective caesarean section, aged between 18–36years, belonging to ASA I or II were randomly divided into 3 groups after considering the inclusion & exclusion criteria.Group A recieved Inj Bupivacaine hyperbaric 7.5 mg (0.5%), Group B: Inj. Bupivacaine hyperbaric 8.75 mg (0.5%) & Group C: Inj. Bupivacaine hyperbaric 10 mg (0.5%). All the observations were recorded and the results were analysed and data are presented as mean ± S.D. for compå data between three groups. ANOVA test was used and р values <0.05 were interpreted as clinically significant. RESULTS: The demographic data was comparable in all the 3 groups. The onset of sensory block was 7.30±087 min in group A, 6.78±0.29 min in group B & 5.31±0.56min in group C. Onset of motor block was 6.18±0.31min in group A, 5.30±0.82min in group B & 4.67±0.34min in group C. Duration of sensory block was 137.77±18.80min in group A, 166.65±22.98min in group B & 184.67±24.74 in group C. CONCLUSION: Increasing the dose of bupivacaine has faster onset and prolong the duration of sensory and motor blockade. There is increased incidence of hypotension, nausea and vomiting with increased dose of bupivacaine. In lower doses there is increased haemodynamic stability & early post–op ambulation at cost of Intraoperative pain and need of general anaesthesia in some cases.