COMPARITIVE STUDY ON TWO DOSES OF CLONIDINE ADDED TO HYPERBARIC BUPIVACAINE IN SPINAL ANAESTHESIA

Dr. Kayalvizhi K B; Dr. N Krishnan

Volume : VIII, Issue : IX, September - 2019

COMPARITIVE STUDY ON TWO DOSES OF CLONIDINE ADDED TO HYPERBARIC BUPIVACAINE IN SPINAL ANAESTHESIA

Dr. Kayalvizhi K B, Dr. N Krishnan

Abstract :

BACKGROUND: Various adjuvants have been added to bupivacaine to prolong duration in spinal Anesthesia. Aim of our study is to compare two doses of clonidine (40mcg and 60mcg) added to 0.5% hyperbaric bupivacaine 2.75ml intrathecally for sub umbilical surgeries. MATERIALS AND METHODS :60 patients enrolled in the study are divided into 3 groups of 20 each. Group B received 2.75ml of 0.5% hyperbaric bupivacaine with 0.4ml saline. Group C1 received 2.75ml of hyperbaric bupivacaine with 40mcg of clonidine. Group C2 received 2.75ml of hyperbaric bupivacaine with 60mcg of clonidine. The groups were comparable with respect to age, height and weight. The onset of sensory and motor block was faster in group C2 compared to other groups. The duration of analgesia is definitively more in group C2. CONCLUSION: 60 mcg of clonidine added to bupivacaine is a better adjuvant in prolonging sensory and motor block intra operatively and duration of effective post–operative analgesia compared to 40 mcg without significant adverse effects.