Correlation between mitotic and ki-67 labelling index in paraffin embedded cervical carcinoma

Dr Chaitali Gupta; Dr Meenakshi Pathak

Volume : VII, Issue : IX, September - 2018

Correlation between mitotic and ki-67 labelling index in paraffin embedded cervical carcinoma

Dr Chaitali Gupta, Dr Meenakshi Pathak

Abstract :

Introduction:In India cervical cancer is the second most frequent cancer among women. This study was carried out to study the role and correlation of ki–67 labelling index and mitotic index in the cervical carcinoma.Methods: The present study was carried out on 40 cases of cervical carcinoma in 39 cervical biopsies and one hysterectomy specimensover a period of three years in the deparment of pathology F H medical college, Tundla, Firozabad, Uttar Pradesh, India. In all cases mitotic index and ki–67 labelling index were calculated.Results: ki–67 labelling index and mitotic index were found to be correlated with each other and increase with the increasing grade of the cervical cancer.Conclusion: Both the proliferative indices, mitotic index and ki–67 labelling indices are useful in determining the grading of cervical cancer.