Correlation between Serum Cortisol Level with CURB-65 score at Hospital Admission in Community-Acquired Pneumonia Patients In Haji Adam Malik General Hospital Medan

Gusti Nugroho; Alwinsyah Abidin; Santi Syafril

Volume : VII, Issue : XI, November - 2018

Correlation between Serum Cortisol Level with CURB-65 score at Hospital Admission in Community-Acquired Pneumonia Patients In Haji Adam Malik General Hospital Medan

Gusti Nugroho, Alwinsyah Abidin, Santi Syafril

Abstract :

Background : Community–acquired pneumonia (CAP) is one of the most common infectious disease and remains associated with high rates of morbidity and mortality worldwide. Optimal risk stratification remains to be evaluated. Currently, several biomarkers and prognostic scores have been evaluated to predict pognosis in CAP. The cortisol level on admission can be a useful biomarker for CAP prognosis. Method : The study design is cross sectional correlation analytic study that involved 40 patients with signs and symptoms of CAP. Result: From 40 samples, 23 male (57.5%) and 17 female (42.5%). There was significant difference of serum cortisol level between mild and high risk CAP ( p < 0.001). Serum cortisol level and CURB–65 score are strongly positive correlated with correlation cefficient (r) 0.919, p < 0.001. A total 40 isolates were successfully isolated from blood samples with highest prevalence of Klebsiella pneumonia (22.5%), Acinetobacter baumannii (15%) followed by E.coli (10%), Burkhlderia cepacia (5%). Conclusion:Serum cortisol level correlates to severity of CAP patients assessed by CURB–65 score.