Demographic profile and haematological changes in Plasmodium falciparum malaria cases in northern India

Dr. Shilpa Mittal; Dr. Praveen Mangal

Volume : VIII, Issue : V, May - 2019

Demographic profile and haematological changes in Plasmodium falciparum malaria cases in northern India

Dr. Shilpa Mittal, Dr. Praveen Mangal

Abstract :

Background and Objectives: Malaria continues to be a great health problem in some of the most populated areas of the world & continues to cause significant morbidity and mortality worldwide. In this study we aimed to study the demographic profile and hematological parameters in falciparum malaria cases. Materials and methods: This open prospective study was conducted in the Department of Medicine, in a tertiary health care centre of northern India. This study was comprised of 100 consecutive patients of P. falciparum malaria who were admitted here. The detailed history and clinical examination of all included patients were done. All the patients were investigated such as CBC, peripheral blood smear (thin & thick) for M.P., blood sugar, S. bilirubin, SGOT, SGPT, urea, creatinine, s. proteins, S. electrolytes, x–ray chest, ABG if needed. Microscopic examination of blood films is accepted as the current universal "Gold standard" for the diagnosis of malaria. Results: Maximum cases were in 20–30 yrs (36%) age group followed by >40 yrs age group (28%). Out of 100 cases, 65 patients were males and 35 were females. The maximum female were of 20–30 yrs. age group (54.28%) and maximum males were more than 40 yrs. age (35.38%). Maximum cases of complicated malaria & uncomplicated malaria were in 20–30 yrs age group i.e. 30.43% and 40.74% respectively. Maximum incidence of falciparum malaria were between July–Oct. Out of 10 patients who died, 5 patient had leucocytosis and 3 patient had severe thrombocytopenia. Conclusion: Studying the demographic profile and haematological parameters will help the clinician in establishing early therapeutic measures, thus preventing the morbidity and mortality