Determination of the seroprevalence of transfusion-transmissible infections (TTIs) among healthy blood donors in a tertiary care hospital in north India

Dr Pramod Kumar Rai

Volume : VIII, Issue : VII, July - 2019

Determination of the seroprevalence of transfusion-transmissible infections (TTIs) among healthy blood donors in a tertiary care hospital in north India

Dr Pramod Kumar Rai

Abstract :

Objective: To determine the sero–prevalence of TTIs among healthy blood donors in a tertiary care hospital in north India. Methods: This was a retrospective study. Blood bank donor cards were used as a source of information. HIV, HCV tests were done by enzyme–linked immunosorbent assay (ELISA) procedure using the third generation kits. Syphilis was diagnosed by performing the standard laboratory test. Malaria testing was done by slide method using Leishman‘s staining. Blood donors were selected if they fulfilled all the criteria to be eligible for donation as described by the standard operating procedure of institution’s blood bank. Results: About half of donors were between 18–25 years of age (49.5%). Majority of donors were males (71.2%). 36.3% were students. Majority of donors were voluntary donors (80.2%). Most of the donors were first time donors (41.6%) followed by second (30.7%), third time (17.5%) and four & above (10.2%). The overall sero–prevalence of infections was 5.9%. The sero–prevalence of HCV was found to be higher (1.8%) than HBV & syphilis (1.2%), HIV (0.9%) and malaria (0.7%) Conclusion: The study reflects the sero–prevalence of the general population in the study area which may be helpful in planning public health interventional strategies.